FolamiRs: Ligand-targeted, vehicle-free delivery of microRNAs for the treatment of cancer

MicroRNAs are small RNAs that negatively regulate gene expression posttranscriptionally. Because changes in microRNA expression can promote or maintain disease states, microRNA-based therapeutics are being evaluated extensively. Unfortunately, the therapeutic potential of microRNA replacement is lim...

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Bibliographic Details
Published in:Sci Transl Med
Main Authors: Orellana, Esteban A., Tenneti, Srinivasarao, Rangasamy, Loganathan, Lyle, L. Tiffany, Low, Philip S., Kasinski, Andrea L.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576188/
https://ncbi.nlm.nih.gov/pubmed/28768807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aam9327
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