Mycobacterium tuberculosis proteasomal ATPase Mpa has a β-grasp domain that hinders docking with the proteasome core protease

Mycobacterium tuberculosis (Mtb) has a proteasome system that is essential for its ability to cause lethal infections in mice. A key component of the system is the proteasomal adenosine triphosphatase (ATPase) Mpa, which captures, unfolds, and translocates protein substrates into the Mtb proteasome...

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Publicado no:Mol Microbiol
Main Authors: Wu, Yujie, Hu, Kuan, Li, Defeng, Bai, Lin, Yang, Shaoqing, Jastrab, Jordan B., Xiao, Shuhao, Hu, Yonglin, Zhang, Susan, Heran Darwin, K., Wang, Tao, Li, Huilin
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575984/
https://ncbi.nlm.nih.gov/pubmed/28419599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13695
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