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Formation and Structure of Wild Type Huntingtin Exon-1 Fibrils
The fact that the heritable neurodegenerative disorder Huntington’s Disease (HD) is autosomal dominant means that there is one wild type and one mutant allele in most HD patients. The CAG repeat expansion in the exon 1 of the protein huntingtin (HTT(ex1)) that causes the disease, leads to the format...
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| 出版年: | Biochemistry |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5575822/ https://ncbi.nlm.nih.gov/pubmed/28621522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00138 |
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