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Solid-State Nuclear Magnetic Resonance on the Static and Dynamic Domains of Huntingtin Exon-1 Fibrils
Amyloid-like fibrils formed by huntingtin exon-1 (htt(ex1)) are a hallmark of Huntington's Disease (HD). The structure of these fibrils is unknown and determining their structure is an important step towards understanding the misfolding processes that cause HD. In HD a polyglutamine (polyQ) dom...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4770890/ https://ncbi.nlm.nih.gov/pubmed/26020223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00281 |
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