Llwytho...

Solid-State Nuclear Magnetic Resonance on the Static and Dynamic Domains of Huntingtin Exon-1 Fibrils

Amyloid-like fibrils formed by huntingtin exon-1 (htt(ex1)) are a hallmark of Huntington's Disease (HD). The structure of these fibrils is unknown and determining their structure is an important step towards understanding the misfolding processes that cause HD. In HD a polyglutamine (polyQ) dom...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochemistry
Prif Awduron: Isas, J. Mario, Langen, Ralf, Siemer, Ansgar B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770890/
https://ncbi.nlm.nih.gov/pubmed/26020223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00281
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!