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Targeting neoantigens to augment antitumour immunity

The past decade of cancer research has been marked by a growing appreciation of the role of immunity in cancer. Mutations in the tumour genome can cause tumours to express mutant proteins that are tumour specific and not expressed on normal cells (neoantigens). These neoantigens are an attractive im...

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Detalhes bibliográficos
Publicado no:Nat Rev Cancer
Main Authors: Yarchoan, Mark, Johnson, Burles A., Lutz, Eric R., Laheru, Daniel A., Jaffee, Elizabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575801/
https://ncbi.nlm.nih.gov/pubmed/28233802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc.2016.154
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