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Erdj3 Has an Essential Role for Z Variant Alpha‐1‐Antitrypsin Degradation
Alpha‐1‐antitrypsin deficiency (AATD) is an inherited disease characterized by emphysema and liver disease. AATD is most often caused by a single amino acid substitution at amino acid 342 in the mature protein, resulting in the Z mutation of the alpha‐1‐antitrypsin gene (ZAAT). This substitution is...
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| Publicado no: | J Cell Biochem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5575529/ https://ncbi.nlm.nih.gov/pubmed/28419579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.26069 |
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