Semi-synthetic vNAR libraries screened against therapeutic antibodies primarily deliver anti-idiotypic binders

Anti-idiotypic binders which specifically recognize the variable region of monoclonal antibodies have proven to be robust tools for pharmacokinetic studies of antibody therapeutics and for the development of cancer vaccines. In the present investigation, we focused on the identification of anti-idio...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Könning, Doreen, Rhiel, Laura, Empting, Martin, Grzeschik, Julius, Sellmann, Carolin, Schröter, Christian, Zielonka, Stefan, Dickgießer, Stephan, Pirzer, Thomas, Yanakieva, Desislava, Becker, Stefan, Kolmar, Harald
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575089/
https://ncbi.nlm.nih.gov/pubmed/28852148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10513-9
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