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Structural insights and biomedical potential of IgNAR scaffolds from sharks

In addition to antibodies with the classical composition of heavy and light chains, the adaptive immune repertoire of sharks also includes a heavy-chain only isotype, where antigen binding is mediated exclusively by a small and highly stable domain, referred to as vNAR. In recent years, due to their...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Zielonka, Stefan, Empting, Martin, Grzeschik, Julius, Könning, Doreen, Barelle, Caroline J, Kolmar, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622739/
https://ncbi.nlm.nih.gov/pubmed/25523873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19420862.2015.989032
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