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Structural insights and biomedical potential of IgNAR scaffolds from sharks

In addition to antibodies with the classical composition of heavy and light chains, the adaptive immune repertoire of sharks also includes a heavy-chain only isotype, where antigen binding is mediated exclusively by a small and highly stable domain, referred to as vNAR. In recent years, due to their...

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Dades bibliogràfiques
Publicat a:MAbs
Autors principals: Zielonka, Stefan, Empting, Martin, Grzeschik, Julius, Könning, Doreen, Barelle, Caroline J, Kolmar, Harald
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622739/
https://ncbi.nlm.nih.gov/pubmed/25523873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19420862.2015.989032
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