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Ordered rearrangement of immunoglobulin heavy chain variable region segments.

The immunoglobulin heavy chain variable region is encoded as three separate libraries of elements in germ-line DNA: VH, D and JH. To examine the order and regulation of their joining, we have developed assays that distinguish their various combinations and have used the assays to study tumor cell an...

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Библиографические подробности
Опубликовано в: :EMBO J
Главные авторы: Alt, F W, Yancopoulos, G D, Blackwell, T K, Wood, C, Thomas, E, Boss, M, Coffman, R, Rosenberg, N, Tonegawa, S, Baltimore, D
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 1984
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC557501/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6086308/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1984.tb01955.x
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