Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions.

A chromosomal segment with a unique structure around the immunoglobulin heavy chain joining region (JH) has been molecularly cloned from an Abelson murine leukemia virus-transformed cell line. Attached to JH3 in the cloned DNA, in inverted sequence, is the DNA from JH1 to the JH2 recognition sequenc...

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Bibliographic Details
Main Authors: Alt, F W, Baltimore, D
Format: Artigo
Language:Inglês
Published: 1982
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC346588/
https://ncbi.nlm.nih.gov/pubmed/6287467
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