Ordered rearrangement of immunoglobulin heavy chain variable region segments.

The immunoglobulin heavy chain variable region is encoded as three separate libraries of elements in germ-line DNA: VH, D and JH. To examine the order and regulation of their joining, we have developed assays that distinguish their various combinations and have used the assays to study tumor cell an...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Alt, F W, Yancopoulos, G D, Blackwell, T K, Wood, C, Thomas, E, Boss, M, Coffman, R, Rosenberg, N, Tonegawa, S, Baltimore, D
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 1984
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC557501/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6086308/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1984.tb01955.x
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