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Physical linkage of a human immunoglobulin heavy chain variable region gene segment to diversity and joining region elements.

Antibody genes are assembled from a series of germ-line gene segments that are juxtaposed during the maturation of B lymphocytes. Although diversification of the adult antibody repertoire results in large part from the combinatorial joining of these gene segments, a restricted set of antibody heavy...

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Autores principales: Schroeder, H W, Walter, M A, Hofker, M H, Ebens, A, Willems van Dijk, K, Liao, L C, Cox, D W, Milner, E C, Perlmutter, R M
Formato: Artigo
Lenguaje:Inglês
Publicado: 1988
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC282394/
https://ncbi.nlm.nih.gov/pubmed/3141924
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