Physical linkage of a human immunoglobulin heavy chain variable region gene segment to diversity and joining region elements.

Antibody genes are assembled from a series of germ-line gene segments that are juxtaposed during the maturation of B lymphocytes. Although diversification of the adult antibody repertoire results in large part from the combinatorial joining of these gene segments, a restricted set of antibody heavy...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Schroeder, H W, Walter, M A, Hofker, M H, Ebens, A, Willems van Dijk, K, Liao, L C, Cox, D W, Milner, E C, Perlmutter, R M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282394/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3141924/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.21.8196
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