Physical linkage of a human immunoglobulin heavy chain variable region gene segment to diversity and joining region elements.

Antibody genes are assembled from a series of germ-line gene segments that are juxtaposed during the maturation of B lymphocytes. Although diversification of the adult antibody repertoire results in large part from the combinatorial joining of these gene segments, a restricted set of antibody heavy...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Schroeder, H W, Walter, M A, Hofker, M H, Ebens, A, Willems van Dijk, K, Liao, L C, Cox, D W, Milner, E C, Perlmutter, R M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282394/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3141924/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.21.8196
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