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Break-induced replication links microsatellite expansion to complex genome rearrangements
The instability of microsatellite DNA repeats is responsible for at least forty neurodegenerative diseases. Recently, Mirkin and colleagues presented a novel mechanism for microsatellite expansions based on break-induced replication (BIR) at sites of microsatellite-induced replication stalling and f...
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| I publikationen: | Bioessays |
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| Huvudupphovsman: | |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2017
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5573876/ https://ncbi.nlm.nih.gov/pubmed/28621832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201700025 |
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