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Complex Chromosomal Rearrangements Mediated by Break-Induced Replication Involve Structure-Selective Endonucleases

DNA double-strand break (DSB) repair occurring in repeated DNA sequences often leads to the generation of chromosomal rearrangements. Homologous recombination normally ensures a faithful repair of DSBs through a mechanism that transfers the genetic information of an intact donor template to the brok...

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Detalhes bibliográficos
Main Authors: Pardo, Benjamin, Aguilera, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459980/
https://ncbi.nlm.nih.gov/pubmed/23071463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002979
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