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Smc5-Smc6 complex suppresses gross chromosomal rearrangements mediated by break-induced replications

Translocations in chromosomes alter genetic information. Although the frequent translocations observed in many tumors suggest the altered genetic information by translocation could promote tumorigenesis, the mechanisms for how translocations are suppressed and produced are poorly understood. The smc...

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Détails bibliographiques
Auteurs principaux: Hwang, Ji-Young, Smith, Stephanie, Ceschia, Audrey, Torres-Rosell, Jordi, Aragon, Luis, Myung, Kyungjae
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585499/
https://ncbi.nlm.nih.gov/pubmed/18585101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.05.006
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