Smc5-Smc6 complex suppresses gross chromosomal rearrangements mediated by break-induced replications

Translocations in chromosomes alter genetic information. Although the frequent translocations observed in many tumors suggest the altered genetic information by translocation could promote tumorigenesis, the mechanisms for how translocations are suppressed and produced are poorly understood. The smc...

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Main Authors: Hwang, Ji-Young, Smith, Stephanie, Ceschia, Audrey, Torres-Rosell, Jordi, Aragon, Luis, Myung, Kyungjae
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585499/
https://ncbi.nlm.nih.gov/pubmed/18585101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.05.006
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