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Smc5-Smc6 complex suppresses gross chromosomal rearrangements mediated by break-induced replications
Translocations in chromosomes alter genetic information. Although the frequent translocations observed in many tumors suggest the altered genetic information by translocation could promote tumorigenesis, the mechanisms for how translocations are suppressed and produced are poorly understood. The smc...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2585499/ https://ncbi.nlm.nih.gov/pubmed/18585101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.05.006 |
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