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Smc5-Smc6 complex suppresses gross chromosomal rearrangements mediated by break-induced replications

Translocations in chromosomes alter genetic information. Although the frequent translocations observed in many tumors suggest the altered genetic information by translocation could promote tumorigenesis, the mechanisms for how translocations are suppressed and produced are poorly understood. The smc...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Hwang, Ji-Young, Smith, Stephanie, Ceschia, Audrey, Torres-Rosell, Jordi, Aragon, Luis, Myung, Kyungjae
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585499/
https://ncbi.nlm.nih.gov/pubmed/18585101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.05.006
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