Smc5-Smc6 complex suppresses gross chromosomal rearrangements mediated by break-induced replications

Translocations in chromosomes alter genetic information. Although the frequent translocations observed in many tumors suggest the altered genetic information by translocation could promote tumorigenesis, the mechanisms for how translocations are suppressed and produced are poorly understood. The smc...

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Bibliografiska uppgifter
Huvudupphovsmän: Hwang, Ji-Young, Smith, Stephanie, Ceschia, Audrey, Torres-Rosell, Jordi, Aragon, Luis, Myung, Kyungjae
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585499/
https://ncbi.nlm.nih.gov/pubmed/18585101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.05.006
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