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Neonatal umbilical cord blood transplantation halts skeletal disease progression in the murine model of MPS-I

Umbilical cord blood (UCB) is a promising source of stem cells to use in early haematopoietic stem cell transplantation (HSCT) approaches for several genetic diseases that can be diagnosed at birth. Mucopolysaccharidosis type I (MPS-I) is a progressive multi-system disorder caused by deficiency of l...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Azario, Isabella, Pievani, Alice, Del Priore, Federica, Antolini, Laura, Santi, Ludovica, Corsi, Alessandro, Cardinale, Lucia, Sawamoto, Kazuki, Kubaski, Francyne, Gentner, Bernhard, Bernardo, Maria Ester, Valsecchi, Maria Grazia, Riminucci, Mara, Tomatsu, Shunji, Aiuti, Alessandro, Biondi, Andrea, Serafini, Marta
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573317/
https://ncbi.nlm.nih.gov/pubmed/28842642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09958-9
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