A Semisynthetic Streptococcus pneumoniae Serotype 8 Glycoconjugate Vaccine

Glycoconjugate vaccines based on capsular polysaccharides (CPSs) of pathogenic bacteria such as Streptococcus pneumoniae successfully protect from disease, but suffer from incomplete coverage, are troublesome to manufacture from isolated CPSs and lack efficacy against certain serotypes. Defined, syn...

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Опубликовано в: :Sci Transl Med
Главные авторы: Schumann, Benjamin, Hahm, Heung Sik, Parameswarappa, Sharavathi G., Reppe, Katrin, Wahlbrink, Annette, Govindan, Subramanian, Kaplonek, Paulina, Pirofski, Liise-anne, Witzenrath, Martin, Anish, Chakkumkal, Pereira, Claney L., Seeberger, Peter H.
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573155/
https://ncbi.nlm.nih.gov/pubmed/28275152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaf5347
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