A Semisynthetic Streptococcus pneumoniae Serotype 8 Glycoconjugate Vaccine

Glycoconjugate vaccines based on capsular polysaccharides (CPSs) of pathogenic bacteria such as Streptococcus pneumoniae successfully protect from disease, but suffer from incomplete coverage, are troublesome to manufacture from isolated CPSs and lack efficacy against certain serotypes. Defined, syn...

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Publicado en:Sci Transl Med
Autores principales: Schumann, Benjamin, Hahm, Heung Sik, Parameswarappa, Sharavathi G., Reppe, Katrin, Wahlbrink, Annette, Govindan, Subramanian, Kaplonek, Paulina, Pirofski, Liise-anne, Witzenrath, Martin, Anish, Chakkumkal, Pereira, Claney L., Seeberger, Peter H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573155/
https://ncbi.nlm.nih.gov/pubmed/28275152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaf5347
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