A Semisynthetic Streptococcus pneumoniae Serotype 8 Glycoconjugate Vaccine

Glycoconjugate vaccines based on capsular polysaccharides (CPSs) of pathogenic bacteria such as Streptococcus pneumoniae successfully protect from disease, but suffer from incomplete coverage, are troublesome to manufacture from isolated CPSs and lack efficacy against certain serotypes. Defined, syn...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Schumann, Benjamin, Hahm, Heung Sik, Parameswarappa, Sharavathi G., Reppe, Katrin, Wahlbrink, Annette, Govindan, Subramanian, Kaplonek, Paulina, Pirofski, Liise-anne, Witzenrath, Martin, Anish, Chakkumkal, Pereira, Claney L., Seeberger, Peter H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573155/
https://ncbi.nlm.nih.gov/pubmed/28275152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaf5347
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