Development of an Efficacious, Semisynthetic Glycoconjugate Vaccine Candidate against Streptococcus pneumoniae Serotype 1

[Image: see text] Infections with Streptococcus pneumoniae are a major health burden. Glycoconjugate vaccines based on capsular polysaccharides (CPSs) successfully protect from infection, but not all pneumococcal serotypes are covered with equal potency. Marketed glycoconjugate vaccines induce low l...

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Publicado en:ACS Cent Sci
Autores principales: Schumann, Benjamin, Reppe, Katrin, Kaplonek, Paulina, Wahlbrink, Annette, Anish, Chakkumkal, Witzenrath, Martin, Pereira, Claney L., Seeberger, Peter H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2018
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879475/
https://ncbi.nlm.nih.gov/pubmed/29632881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.7b00504
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