A semi-synthetic oligosaccharide conjugate vaccine candidate confers protection against Streptococcus pneumoniae serotype 3 infection

The identification of immunogenic glycotopes that render glycoconjugate vaccines protective is key to improving vaccine efficacy. Synthetic oligosaccharides are an attractive alternative to the heterogeneous preparations of purified polysaccharides that most marketed glycoconjugate vaccines are base...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Chem Biol
Prif Awduron: Parameswarappa, Sharavathi Guddehalli, Reppe, Katrin, Geissner, Andreas, Ménová, Petra, Govindan, Subramanian, Calow, Adam D. J., Wahlbrink, Annette, Weishaupt, Markus W., Monnanda, Bopanna Ponnappa, Bell, Roland Lawrence, Pirofski, Liise-anne, Suttorp, Norbert, Sander, Leif Erik, Witzenrath, Martin, Pereira, Claney Lebev, Anish, Chakkumkal, Seeberger, Peter H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5234679/
https://ncbi.nlm.nih.gov/pubmed/27818299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2016.09.016
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