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Applications of Quantum Mechanical/Molecular Mechanical methods to the chemical insertion step of DNA and RNA polymerization
We review theoretical attempts to model the chemical insertion reactions of nucleoside triphosphates catalyzed by the nucleic acid polymerases using combined quantum mechanical/molecular mechanical methodology. Due to an existing excellent database of high resolution x-ray crystal structures, the DN...
में बचाया:
| में प्रकाशित: | Adv Protein Chem Struct Biol |
|---|---|
| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2014
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5573153/ https://ncbi.nlm.nih.gov/pubmed/25458356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.apcsb.2014.10.001 |
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