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Applications of Quantum Mechanical/Molecular Mechanical methods to the chemical insertion step of DNA and RNA polymerization

We review theoretical attempts to model the chemical insertion reactions of nucleoside triphosphates catalyzed by the nucleic acid polymerases using combined quantum mechanical/molecular mechanical methodology. Due to an existing excellent database of high resolution x-ray crystal structures, the DN...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Adv Protein Chem Struct Biol
Egile Nagusiak: Perera, Lalith, Beard, William A., Pedersen, Lee G., Wilson, Samuel H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573153/
https://ncbi.nlm.nih.gov/pubmed/25458356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.apcsb.2014.10.001
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