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Demethylation of induced pluripotent stem cells from type 1 diabetic patients enhances differentiation into functional pancreatic β cells

Type 1 diabetes (T1D) can be managed by transplanting either the whole pancreas or isolated pancreatic islets. However, cadaveric pancreas is scarcely available for clinical use, limiting this approach. As such, there is a great need to identify alternative sources of clinically usable pancreatic ti...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Manzar, Gohar S., Kim, Eun-Mi, Zavazava, Nicholas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572901/
https://ncbi.nlm.nih.gov/pubmed/28360105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.784280
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