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Demethylation of induced pluripotent stem cells from type 1 diabetic patients enhances differentiation into functional pancreatic β cells

Type 1 diabetes (T1D) can be managed by transplanting either the whole pancreas or isolated pancreatic islets. However, cadaveric pancreas is scarcely available for clinical use, limiting this approach. As such, there is a great need to identify alternative sources of clinically usable pancreatic ti...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Manzar, Gohar S., Kim, Eun-Mi, Zavazava, Nicholas
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572901/
https://ncbi.nlm.nih.gov/pubmed/28360105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.784280
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