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Demethylation of induced pluripotent stem cells from type 1 diabetic patients enhances differentiation into functional pancreatic β cells

Type 1 diabetes (T1D) can be managed by transplanting either the whole pancreas or isolated pancreatic islets. However, cadaveric pancreas is scarcely available for clinical use, limiting this approach. As such, there is a great need to identify alternative sources of clinically usable pancreatic ti...

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Vydáno v:J Biol Chem
Hlavní autoři: Manzar, Gohar S., Kim, Eun-Mi, Zavazava, Nicholas
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572901/
https://ncbi.nlm.nih.gov/pubmed/28360105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.784280
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