Comparison of Plasma and Intrapulmonary Concentrations of Nafithromycin (WCK 4873) in Healthy Adult Subjects

The nafithromycin concentrations in the plasma, epithelial lining fluid (ELF), and alveolar macrophages (AM) of 37 healthy adult subjects were measured following repeated dosing of oral nafithromycin at 800 mg once daily for 3 days. The values of noncompartmental pharmacokinetic (PK) parameters were...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Rodvold, Keith A., Gotfried, Mark H., Chugh, Rakesh, Gupta, Mugdha, Friedland, H. David, Bhatia, Ashima
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571338/
https://ncbi.nlm.nih.gov/pubmed/28696231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01096-17
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