Comparison of Plasma and Intrapulmonary Concentrations of Nafithromycin (WCK 4873) in Healthy Adult Subjects

The nafithromycin concentrations in the plasma, epithelial lining fluid (ELF), and alveolar macrophages (AM) of 37 healthy adult subjects were measured following repeated dosing of oral nafithromycin at 800 mg once daily for 3 days. The values of noncompartmental pharmacokinetic (PK) parameters were...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Rodvold, Keith A., Gotfried, Mark H., Chugh, Rakesh, Gupta, Mugdha, Friedland, H. David, Bhatia, Ashima
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571338/
https://ncbi.nlm.nih.gov/pubmed/28696231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01096-17
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