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Plasma and Intrapulmonary Concentrations of ETX2514 and Sulbactam following Intravenous Administration of ETX2514SUL to Healthy Adult Subjects

ETX2514 is a novel β-lactamase inhibitor that broadly inhibits Ambler class A, C, and D β-lactamases. ETX2514 combined with sulbactam (SUL) in vitro restores sulbactam activity against Acinetobacter baumannii. ETX2514-sulbactam (ETX2514SUL) is under development for the treatment of A. baumannii infe...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Rodvold, Keith A., Gotfried, Mark H., Isaacs, Robin D., O'Donnell, John P., Stone, Emily
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201107/
https://ncbi.nlm.nih.gov/pubmed/30126953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01089-18
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