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Combined Effect of the Cfr Methyltransferase and Ribosomal Protein L3 Mutations on Resistance to Ribosome-Targeting Antibiotics

Several groups of antibiotics inhibit bacterial growth by binding to bacterial ribosomes. Mutations in ribosomal protein L3 have been associated with resistance to linezolid and tiamulin, which both bind at the peptidyl transferase center in the ribosome. Resistance to these and other antibiotics al...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Pakula, Kevin K., Hansen, Lykke H., Vester, Birte
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571294/
https://ncbi.nlm.nih.gov/pubmed/28630201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00862-17
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