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Optogenetic regulation of insulin secretion in pancreatic β-cells

Pancreatic β-cell insulin production is orchestrated by a complex circuitry involving intracellular elements including cyclic AMP (cAMP). Tackling aberrations in glucose-stimulated insulin release such as in diabetes with pharmacological agents, which boost the secretory capacity of β-cells, is link...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Fan, Tzanakakis, Emmanuel S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571193/
https://ncbi.nlm.nih.gov/pubmed/28839233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09937-0
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