The hepatocyte-specific HNF4α/miR-122 pathway contributes to iron overload–mediated hepatic inflammation

Hepatic iron overload (IO) is a major complication of transfusional therapy. It was generally thought that IO triggers substantial inflammatory responses by producing reactive oxygen species in hepatic macrophages. Recently, a decrease in microRNA-122 (miR-122) expression was observed in a genetic k...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Blood
Huvudupphovsmän: Li, Min, Tang, Yuxiao, Wu, Lusha, Mo, Fengfeng, Wang, Xin, Li, Hongxia, Qi, Ruirui, Zhang, Hongwei, Srivastava, Arun, Ling, Chen
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2017
Ämnen:
Red Cells, Iron, and Erythropoiesis
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570677/
https://ncbi.nlm.nih.gov/pubmed/28655781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-12-755967
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk