CCL2 is Upregulated by Decreased miR-122 Expression in Iron-Overload-Induced Hepatic Inflammation

Background/Aims: Iron overload (IO) is accompanied by hepatic inflammation. The chemokine (C-C motif) ligand 2 (CCL2) mediates inflammation, and its overexpression is associated with IO. However, whether IO results in CCL2 overexpression in the liver and the underlying mechanisms are unclear. Method...

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Detalhes bibliográficos
Main Authors: Yuxiao Tang, Wentao Jia, Xiaowen Niu, Lusha Wu, Hui Shen, Lina Wang, Ruirui Qi, Changquan Ling, Min Li
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Physiol Biochem Press GmbH & Co KG 2017-11-01
Colecção:Cellular Physiology and Biochemistry
Assuntos:
Iron overload
Hepatic inflammation
Chemokine (C-C motif) ligand 2 (CCL2)
miR-122
Acesso em linha:https://www.karger.com/Article/FullText/485355
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