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A c-Myb mutant causes deregulated differentiation due to impaired histone binding and abrogated pioneer factor function
The transcription factor c-Myb is involved in early differentiation and proliferation of haematopoietic cells, where it operates as a regulator of self-renewal and multi-lineage differentiation. Deregulated c-Myb plays critical roles in leukaemias and other human cancers. Due to its role as a master...
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| Vydáno v: | Nucleic Acids Res |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5570105/ https://ncbi.nlm.nih.gov/pubmed/28472346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx364 |
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