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Human APE2 protein is mostly localized in the nuclei and to some extent in the mitochondria, while nuclear APE2 is partly associated with proliferating cell nuclear antigen

In human cells APE1 is the major AP endonuclease and it has been reported to have no functional mitochondrial targeting sequence (MTS). We found that APE2 protein possesses a putative MTS. When its N-terminal 15 amino acid residues were fused to the N-terminus of green fluorescent protein and transi...

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Bibliographische Detailangaben
Hauptverfasser: Tsuchimoto, Daisuke, Sakai, Yasunari, Sakumi, Kunihiko, Nishioka, Kenichi, Sasaki, Masafumi, Fujiwara, Toshiyuki, Nakabeppu, Yusaku
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2001
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC55700/
https://ncbi.nlm.nih.gov/pubmed/11376153
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