Human APE2 protein is mostly localized in the nuclei and to some extent in the mitochondria, while nuclear APE2 is partly associated with proliferating cell nuclear antigen

In human cells APE1 is the major AP endonuclease and it has been reported to have no functional mitochondrial targeting sequence (MTS). We found that APE2 protein possesses a putative MTS. When its N-terminal 15 amino acid residues were fused to the N-terminus of green fluorescent protein and transi...

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Bibliografiske detaljer
Main Authors:	Tsuchimoto, Daisuke, Sakai, Yasunari, Sakumi, Kunihiko, Nishioka, Kenichi, Sasaki, Masafumi, Fujiwara, Toshiyuki, Nakabeppu, Yusaku
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 2001
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC55700/ https://ncbi.nlm.nih.gov/pubmed/11376153
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Human APE2 protein is mostly localized in the nuclei and to some extent in the mitochondria, while nuclear APE2 is partly associated with proliferating cell nuclear antigen

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