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Role of mTORC1-S6K1 signaling pathway in regulation of hematopoietic stem cell and acute myeloid leukemia

Dysregulation of the mechanistic target of rapamycin complex 1 (mTORC1)-p70 ribosomal protein kinase 1 (S6K1) signaling pathway occurs frequently in acute myeloid leukemia (AML) patients. This pathway also plays a critical role in maintaining normal cellular processes. Given the importance of leukem...

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Pubblicato in:Exp Hematol
Autori principali: Ghosh, Joydeep, Kapur, Reuben
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569945/
https://ncbi.nlm.nih.gov/pubmed/28342808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2017.02.004
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