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Mechanosensitive microRNA-181b regulates aortic valve endothelial matrix degradation by targeting TIMP3
PURPOSE: Calcific aortic valve disease (CAVD) is a major cause of morbidity in the aging population, but underlying mechanisms of its progression remain poorly understood. Aortic valve calcification preferentially occurs on the fibrosa, which is subjected to disturbed flow. The side-specific progres...
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| Publicado en: | Cardiovasc Eng Technol |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5568995/ https://ncbi.nlm.nih.gov/pubmed/28236165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13239-017-0296-z |
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