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In vivo Evaluation of Site-specifically PEGylated Chemically Self-assembled Protein Nanostructures

Chemically Self-Assembled Nanorings (CSANs) are made of dihydrofolate reductase (DHFR) fusion proteins and have been successfully used in vitro for cellular cargo delivery and cell surface engineering applications. However, CSANs have yet to be evaluated for their in vivo stability, circulation and...

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Publicado en:Mol Pharm
Autores principales: Shah, Rachit, Petersburg, Jacob, Gangar, Amit C., Fegan, Adrian, Wagner, Carston R., Kumarapperuma, Sidath C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568902/
https://ncbi.nlm.nih.gov/pubmed/26985775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.6b00110
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