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Programmable Self-Assembly of Antibody-Oligonucleotide Conjugates as Small Molecule and Protein Carriers
Dihydrofolate reductase-single-chain variable fragment (scFv) fusion proteins can be used for the targeted cellular delivery of oligonucleotides, conjugated small molecules and proteins, via labeling of oligonucleotides by bis-methotrexate.
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3312035/ https://ncbi.nlm.nih.gov/pubmed/22296405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja210894g |
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