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Programmable Self-Assembly of Antibody-Oligonucleotide Conjugates as Small Molecule and Protein Carriers

Dihydrofolate reductase-single-chain variable fragment (scFv) fusion proteins can be used for the targeted cellular delivery of oligonucleotides, conjugated small molecules and proteins, via labeling of oligonucleotides by bis-methotrexate.

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Bibliografiska uppgifter
Huvudupphovsmän: Gangar, Amit, Fegan, Adrian, Kumarapperuma, Sidath C., Wagner, Carston R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312035/
https://ncbi.nlm.nih.gov/pubmed/22296405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja210894g
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