Programmable Self-Assembly of Antibody-Oligonucleotide Conjugates as Small Molecule and Protein Carriers

Dihydrofolate reductase-single-chain variable fragment (scFv) fusion proteins can be used for the targeted cellular delivery of oligonucleotides, conjugated small molecules and proteins, via labeling of oligonucleotides by bis-methotrexate.

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Bibliografiske detaljer
Main Authors:	Gangar, Amit, Fegan, Adrian, Kumarapperuma, Sidath C., Wagner, Carston R.
Format:	Artigo
Sprog:	Inglês
Udgivet:	2012
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3312035/ https://ncbi.nlm.nih.gov/pubmed/22296405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja210894g
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Programmable Self-Assembly of Antibody-Oligonucleotide Conjugates as Small Molecule and Protein Carriers

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