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Chemically Self-assembled Antibody Nanostructures (CSANs) as Potential Drug Carriers
Chemically self-assembled antibody nanorings (CSANs) displaying multiple copies of single chain variable fragments (scFv) can be prepared from dihydrofolate reductase (DHFR) fusion proteins and bismethotrexate (BisMTX). We have designed and synthesized a BisMTX chemical dimerizer (bisMTX-NH(2)) that...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3549309/ https://ncbi.nlm.nih.gov/pubmed/23013206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300303k |
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