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Chemically Self-assembled Antibody Nanostructures (CSANs) as Potential Drug Carriers

Chemically self-assembled antibody nanorings (CSANs) displaying multiple copies of single chain variable fragments (scFv) can be prepared from dihydrofolate reductase (DHFR) fusion proteins and bismethotrexate (BisMTX). We have designed and synthesized a BisMTX chemical dimerizer (bisMTX-NH(2)) that...

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Bibliografische gegevens
Hoofdauteurs: Fegan, Adrian, Kumarapperuma, Sidath C., Wagner, Carston R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549309/
https://ncbi.nlm.nih.gov/pubmed/23013206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300303k
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