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Simultaneous Dual Protein Labeling using a Triorthogonal Reagent

Construction of heterofunctional proteins is a rapidly emerging area of biotherapeutics. Combining a protein with other moieties such as a targeting element, a toxic protein or small molecule, a fluorophore or PEG groups, can improve the specificity, functionality, potency, and pharmacokinetic profi...

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Détails bibliographiques
Auteurs principaux: Rashidian, Mohammad, Kumarapperuma, Sidath C., Gabrielse, Kari, Fegan, Adrian, Wagner, Carston R., Distefano, Mark D.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873327/
https://ncbi.nlm.nih.gov/pubmed/24134212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja403813b
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