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Snail transcription factor NLS and importin β1 regulate the subcellular localization of Cathepsin L and Cux1

Several recent studies have highlighted an additional unexpected localization and site of action for Cathepsin L (Cat L) protease within the nucleus in breast, colon and prostate cancer, however, its role in the nucleus was unclear. It was proposed to mediate proteolytic processing of the transcript...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Burton, Liza J., Henderson, Veronica, Liburd, Latiffa, Odero-Marah, Valerie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568889/
https://ncbi.nlm.nih.gov/pubmed/28698143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.07.039
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