Snail promotes cell migration through PI3K/AKT-dependent Rac1 activation as well as PI3K/AKT-independent pathways during prostate cancer progression

Snail, a zinc-finger transcription factor, induces epithelial-mesenchymal transition (EMT), which is associated with increased cell migration and metastasis in cancer cells. Rac1 is a small G-protein which upon activation results in formation of lamellipodia, the first protrusions formed by migratin...

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Detalhes bibliográficos
Publicado no:Cell Adh Migr
Main Authors: Henderson, Veronica, Smith, Basil, Burton, Liza J, Randle, Diandra, Morris, Marisha, Odero-Marah, Valerie A
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594564/
https://ncbi.nlm.nih.gov/pubmed/26207671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336918.2015.1013383
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