Snail promotes cell migration through PI3K/AKT-dependent Rac1 activation as well as PI3K/AKT-independent pathways during prostate cancer progression

Snail, a zinc-finger transcription factor, induces epithelial-mesenchymal transition (EMT), which is associated with increased cell migration and metastasis in cancer cells. Rac1 is a small G-protein which upon activation results in formation of lamellipodia, the first protrusions formed by migratin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Adh Migr
Egile Nagusiak: Henderson, Veronica, Smith, Basil, Burton, Liza J, Randle, Diandra, Morris, Marisha, Odero-Marah, Valerie A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2015
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594564/
https://ncbi.nlm.nih.gov/pubmed/26207671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336918.2015.1013383
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