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CCAAT-displacement protein/cut homeobox transcription factor (CUX1) represses estrogen receptor-alpha (ER-α) in triple-negative breast cancer cells and can be antagonized by muscadine grape skin extract (MSKE)

Triple-Negative Breast Cancers (TNBCs) are the most difficult to treat subtype of breast cancer and are often associated with high nuclear expression of Snail and Cathepsin L (Cat L) protease. We have previously shown that Snail can increase Cat L expression/activity in prostate and breast cancer ce...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Burton, Liza J., Hawsawi, Ohuod, Sweeney, Janae, Bowen, Nathan, Hudson, Tamaro, Odero-Marah, Valerie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6460785/
https://ncbi.nlm.nih.gov/pubmed/30964885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214844
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