Muscadine grape skin extract can antagonize Snail-cathepsin L-mediated invasion, migration and osteoclastogenesis in prostate and breast cancer cells

To develop new and effective chemopreventive agents against bone metastasis, we assessed the effects of muscadine grape skin extract (MSKE), whose main bioactive component is anthocyanin, on bone turnover, using prostate and breast cancer cell models overexpressing Snail transcription factor. MSKE h...

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Pubblicato in:Carcinogenesis
Autori principali: Burton, Liza J., Smith, Basil A., Smith, Bethany N., Loyd, Quentin, Nagappan, Peri, McKeithen, Danielle, Wilder, Catera L., Platt, Manu O., Hudson, Tamaro, Odero-Marah, Valerie A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643647/
https://ncbi.nlm.nih.gov/pubmed/26069256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgv084
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