Muscadine grape skin extract can antagonize Snail-cathepsin L-mediated invasion, migration and osteoclastogenesis in prostate and breast cancer cells

To develop new and effective chemopreventive agents against bone metastasis, we assessed the effects of muscadine grape skin extract (MSKE), whose main bioactive component is anthocyanin, on bone turnover, using prostate and breast cancer cell models overexpressing Snail transcription factor. MSKE h...

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Gepubliceerd in:Carcinogenesis
Hoofdauteurs: Burton, Liza J., Smith, Basil A., Smith, Bethany N., Loyd, Quentin, Nagappan, Peri, McKeithen, Danielle, Wilder, Catera L., Platt, Manu O., Hudson, Tamaro, Odero-Marah, Valerie A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643647/
https://ncbi.nlm.nih.gov/pubmed/26069256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgv084
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